Alessia Di Matteo has died at the age of 18-months. The little girl was born with congenital smooth muscle disorder. The condition, fatal without treatment, doesn't allow the stomach, intestines or kidneys to work properly.
Alessia made the headlines last year when she underwent a 12 hour operation to replace 8 of her internal organs, liver, stomach, pancreas, small intestine, large intestine, spleen and two kidneys. The liver was later replaced again.
Alessia was transferred from a Florida clinic last month to a hospital in her home town of Genoa, Italy in a extremely serious condition.